Original or OE TPMS sensors are pre-programmed for 1 make and type of car, while a universal sensor can control a whole range of makes and types of cars. A universal TPMS sensor can be programmed with a dedicated TPMS tool, with which the protocol of a certain vehicle is programmed on the sensor, so that the sensor can communicate correctly with the car. With an OE TPMS sensor this has already been done by the manufacturer. With both options, the new sensor will have to be "taught" to the vehicle (often) using a TPMS tool. Unless you already have TPMS sensors in your car, you can "clone" the ID numbers of the current sensors to the new, universal sensors. You do not have to re-teach this to the car. This is not possible with OE sensors and you will always have to teach the sensors with the correct teaching procedure.